![]() ![]() VO2 max is measured in how many milliliters of oxygen per kilogram of body mass a person can cycle through each minute (mL/kg/min). The faster the oxygen flow, the more aerobically fit a person is. A person's VO2 max is a measurement of how quickly they use oxygen during aerobic exercise, Weyand said. Marathoners rely on a process known as maximal oxygen uptake, which dictates how much oxygen is delivered to the muscles. For long-distance running, the biggest limitations are cardiac output and oxygen flow. There's disagreement over which body system functions as the ceiling for how fast humans can run, Aaron Baggish, associate director of the Cardiovascular Performance Program at Massachusetts General Hospital and co-medical director for the Boston Marathon, told Live Science.
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